FIIN-1

Chemical Structure : FIIN-1

CAS No.: 1256152-35-8

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货号: PC-28539Not For Human Use, Lab Use Only.

FIIN-1 is a potent, selective and covalent FGFR inhibitor with Kd values of 2.8/6.9/5.4/120 nM and 32/120 nM for FGFR1/2/3/4 and Flt1/4 respectively, inhibits FGFR1/2/3/4 with IC50 of 9.2, 6.2, 11.9, and 189 nM.

规格	价格	库存
5 mg	￥1980	In stock
10 mg	￥3280	In stock
25 mg	￥5280	In stock
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100 mg		Get quote

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生物&药学活性

FIIN-1 is a potent, selective and covalent FGFR inhibitor with Kd values of 2.8/6.9/5.4/120 nM and 32/120 nM for FGFR1/2/3/4 and Flt1/4 respectively, inhibits FGFR1/2/3/4 with IC50 of 9.2, 6.2, 11.9, and 189 nM.

物理化学性质&存储条件

分子量	656.61
分子式	C32H39Cl2N7O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-((3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-((4-(diethylamino)butyl)amino)-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)methyl)phenyl)acrylamide

参考文献

1. Wenjun Zhou, et al. Chem Biol. 2010 Mar 26;17(3):285-95.

FIIN-1

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物理化学性质&存储条件

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FIIN-1

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物理化学性质&存储条件

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