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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-FABP-FABP inhibitor MF6
FABP inhibitor MF6

Chemical Structure : FABP inhibitor MF6

CAS No.: 2136377-16-5

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FABP inhibitor MF6 (FABP ligand 6)

货号: PC-25492Not For Human Use, Lab Use Only.

FABP inhibitor MF6 (FABP ligand 6) is a small molecule ligand / inhibitor of fatty acid-binding proteins (FABPs) with high affinity for FABP7 (Kd=20 nM), with much weaker affinity for FABP3 (Kd=1038 nM) and FABP5 (Kd=874 nM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

FABP inhibitor MF6 (FABP ligand 6) is a small molecule ligand / inhibitor of fatty acid-binding proteins (FABPs) with high affinity for FABP7 (Kd=20 nM), with much weaker affinity for FABP3 (Kd=1038 nM) and FABP5 (Kd=874 nM).

物理化学性质&存储条件

分子量 492.98
分子式 C28H26ClFN2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-(2-(5-(2-chlorophenyl)-1-(4-isopropylphenyl)-1H-pyrazol-3-yl)-4-fluorophenoxy)butanoic acid

参考文献

1. Guo Q, et al. Biomedicines. 2021 May 10;9(5):529.

2. Cheng A., et al. Acta Pharmacol. Sin. 2021;0:1–11.

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