F0608-0019

Chemical Structure : F0608-0019

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货号: PC-24150Not For Human Use, Lab Use Only.

F0608-0019 is a highly potent and selective PI3Kα inhibitor with IC50 of 0.47 uM.

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生物&药学活性

F0608-0019 is a highly potent and selective PI3Kα inhibitor with IC50 of 0.47 uM.
F0608-0019 has minimal impact on PI3Kβ with only a 5% inhibition and a moderate reduction in PI3Kγ activity by 26.9% at 10 uM.
F0608-0019 displays remarkable efficacy in suppressing HCT116 colorectal cancer cell proliferation, with an IC50 of 12.14 uM.

物理化学性质&存储条件

分子量	427.42
分子式	C24H17N3O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-benzoyl-N-(5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1,3,4-oxadiazol-2-yl)benzamide

参考文献

1. Albassam H, et al. J Enzyme Inhib Med Chem. 2025 Dec;40(1):2468852.

F0608-0019

生物&药学活性

物理化学性质&存储条件

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F0608-0019

生物&药学活性

物理化学性质&存储条件

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