Evans Blue | CaMKII-α inhibitor | Probechem Biochemicals

Chemical Structure : Evans Blue

CAS No.: 314-13-6

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Evans Blue (Direct Blue 53, T-1824, C.I. 23860)

货号: PC-24513Not For Human Use, Lab Use Only.

规格	价格	库存
100 mg	￥380	In stock
250 mg	￥580	In stock
1 g		Get quote

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生物&药学活性

Evans Blue is a selective small-molecule inhibitor of CaMKII-alpha (CaMKII-α) with IC50 of 197.1 nM, also is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT).
Evans Blue is a L-glutamate and kainate receptor-mediated currents inhibitor.
Evans Blue has a strong affinity towards serum albumin, as a high molecular weight protein tracer.
Evans Blue is also used to study BBB (blood-brain barrier) permeability.

物理化学性质&存储条件

分子量	960.79
分子式	C34H24N6Na4O14S4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Sodium 6,6'-((3,3'-dimethyl-[1,1'-biphenyl]-4,4'-diyl)bis(diazene-2,1-diyl))bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate)

参考文献

1. Tian J, et al. Cancer Sci. 2025 Apr 4. doi: 10.1111/cas.70051.

2. Linpeng Yao, et al. Contrast Media Mol Imaging. 2018 Apr 22:2018:7628037.

3. Anatol Manaenko, et al. J Neurosci Methods. 2011 Feb 15;195(2):206-10.

Evans Blue (Direct Blue 53, T-1824, C.I. 23860)

生物&药学活性

物理化学性质&存储条件

参考文献

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Evans Blue (Direct Blue 53, T-1824, C.I. 23860)

生物&药学活性

物理化学性质&存储条件

参考文献

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