Erastin | Ferroptosis inducer | Probechem Biochemicals

Chemical Structure : Erastin

CAS No.: 571203-78-6

加入收藏

Erastin (Ferroptosis inducer)

货号: PC-22423Not For Human Use, Lab Use Only.

Erastin is a specific ferroptosis-inducing compound, shows RAS-selective lethality, also targetsvoltage-dependent anion channel 3 (VDAC3).

规格	价格	库存
5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3580	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Erastin is a specific ferroptosis-inducing compound, shows RAS-selective lethality, also targetsvoltage-dependent anion channel 3 (VDAC3).
Erastin inhibits voltage-dependent anion channels (VDAC2/VDAC3) and accelerates oxidation, leading to the accumulation of endogenous reactive oxygen species (ROS).
Erastin also disrupts mitochondrial permeability transition pore (mPTP) with anti-tumor activity.

物理化学性质&存储条件

分子量	547.05
分子式	C30H31ClN4O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(1-(4-(2-(4-Chlorophenoxy)acetyl)piperazin-1-yl)ethyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one

参考文献

1. Dolma S, et al. Cancer Cell. 2003 Mar;3(3):285-96.

2. Sun X, et al. Oncogene. 2015 Nov 5;34(45):5617-25.

3. Yang WS, et al. Chem Biol. 2008 Mar;15(3):234-45.

Erastin (Ferroptosis inducer)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Erastin (Ferroptosis inducer)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.