Erasin | STAT3 inhibitor | Probechem Biochemicals

Chemical Structure : Erasin

CAS No.: 2256056-21-8

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Erasin (STAT3 inhibitor Erasin)

货号: PC-61033Not For Human Use, Lab Use Only.

Erasin is a potent, selective STAT3 inhibitor with IC50 of 9.7 uM, inhibits tyrosine phosphorylation of STAT3 with selectivity over STAT5 and STAT1 in cell-based assays.

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5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥2180	In stock
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生物&药学活性

Erasin is a potent, selective STAT3 inhibitor with IC50 of 9.7 uM, inhibits tyrosine phosphorylation of STAT3 with selectivity over STAT5 and STAT1 in cell-based assays.
Erasin induces apoptosis in Erlotinib-resistant lung cancer cells.

物理化学性质&存储条件

分子量	349.39
分子式	C20H19N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N'-((6-(tert-butyl)-4-oxo-4H-chromen-3-yl)methylene)nicotinohydrazide

参考文献

1. Lis C, et al. Sci Rep. 2017 Dec 12;7(1):17390.

Erasin (STAT3 inhibitor Erasin)

生物&药学活性

物理化学性质&存储条件

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Erasin (STAT3 inhibitor Erasin)

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物理化学性质&存储条件

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