Epothilone D (Utidelone, Desoxyepothilone B, KOS 862) | Microtubule stabilizer

Chemical Structure : Epothilone D

CAS No.: 189453-10-9

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Epothilone D (Utidelone, Desoxyepothilone B, dEpoB, KOS 862)

货号: PC-23848Not For Human Use, Lab Use Only.

Epothilone D (Utidelone, Desoxyepothilone B, KOS 862) is a potent microtubule stabilizer, inhibits CCRF-CEM/VBL1000 cells (2,048-fold resistance to vinblastine) with IC50 of 2.9 nM.

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5 mg	￥1380	In stock
10 mg	￥2180	In stock
25 mg	￥3780	In stock
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100 mg		Get quote

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生物&药学活性

Epothilone D (Utidelone, Desoxyepothilone B, KOS 862) is a potent microtubule stabilizer, inhibits CCRF-CEM/VBL1000 cells (2,048-fold resistance to vinblastine) with IC50 of 2.9 nM.

物理化学性质&存储条件

分子量	491.69
分子式	C27H41NO5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(4S,7R,8S,9S,13Z,16S)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione

参考文献

1. Chou TC, et al. Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):8113-8.

Epothilone D (Utidelone, Desoxyepothilone B, dEpoB, KOS 862)

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物理化学性质&存储条件

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Epothilone D (Utidelone, Desoxyepothilone B, dEpoB, KOS 862)

生物&药学活性

物理化学性质&存储条件

参考文献

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