Eplerenone | Aldosterone receptor antagonist, MR antagonist

首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Mineralocorticoid Receptor (MLR)-Eplerenone

Chemical Structure : Eplerenone

CAS No.: 107724-20-9

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Eplerenone (Epoxymexrenone)

货号: PC-27029Not For Human Use, Lab Use Only.

Eplerenone (Epoxymexrenone) is a selective, orally active aldosterone receptor antagonist, also is a selective mineralocorticoid receptor antagonist with IC50 of 81 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Eplerenone (Epoxymexrenone) is a selective, orally active aldosterone receptor antagonist, also is a selective mineralocorticoid receptor antagonist with IC50 of 81 nM.

物理化学性质&存储条件

分子量	414.50
分子式	C24H30O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Methyl (4aS,4bR,5aR,6aS,7R,9aS,9bR,10R)-4a,6a-dimethyl-2,4'-dioxo-2,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-3H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate

参考文献

1. McMahon EG. Curr Opin Pharmacol. 2001 Apr;1(2):190-6.

2. Delyani JA, et al. Cardiovasc Drug Rev. 2001 Fall;19(3):185-200.

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Eplerenone (Epoxymexrenone)

生物&药学活性

物理化学性质&存储条件

参考文献

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Eplerenone (Epoxymexrenone)

生物&药学活性

物理化学性质&存储条件

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