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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Cyclooxygenase (COX)-Epicatechin
Epicatechin

Chemical Structure : Epicatechin

CAS No.: 490-46-0

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Epicatechin ((-)-Epicatechin, (-)-Epicatechol)

货号: PC-26089Not For Human Use, Lab Use Only.

Epicatechin((-)-Epicatechin, (-)-Epicatechol) is a small molecule inhibitor of cyclooxygenase-1 (COX-1) with IC50 of 3.2 uM, inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB, interacts with and neutralize reactive oxygen species (ROS) in cells.

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100 mg ￥1180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Epicatechin((-)-Epicatechin, (-)-Epicatechol) is a small molecule inhibitor of cyclooxygenase-1 (COX-1) with IC50 of 3.2 uM, inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB, interacts with and neutralize reactive oxygen species (ROS) in cells.

物理化学性质&存储条件

分子量 290.27
分子式 C15H14O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2R,3R)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol

参考文献

1. Shay J, et al. Oxid Med Cell Longev. 2015;2015:181260.

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