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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-Enfiborole
Enfiborole

Chemical Structure : Enfiborole

CAS No.: 2152662-88-7

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Enfiborole

货号: PC-26325Not For Human Use, Lab Use Only.

Enfiborole is a potent small molecule inhibitor of Trypanosoma congolense (T. congolense) and Trypanosoma vivax (T. vivax) parasites with IC50 of 0.14 nM and 0.07 nM respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Enfiborole is a potent small molecule inhibitor of Trypanosoma congolense (T. congolense) and Trypanosoma vivax (T. vivax) parasites with IC50 of 0.14 nM and 0.07 nM respectively.

物理化学性质&存储条件

分子量 450.22
分子式 C21H22BF3N2O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(6-(trifluoromethyl)pyridin-3-yl)methyl (1-hydroxy-7-methyl-1,3-dihydrobenzo[c][1,2]oxaborole-6-carbonyl)-L-valinate

参考文献

1. Akama T, et al. Bioorg Med Chem Lett. 2018 Jan 1;28(1):6-10.

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