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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-Endochin
Endochin

Chemical Structure : Endochin

CAS No.: 354155-51-4

Endochin

货号: PC-24762Not For Human Use, Lab Use Only.

Endochin is an antimalarial agent, inhibits T. gondii growth in vitro (IC50=0.003 nM), inhibits  inhibited T.gondii cytochrome c reduction with IC50 of 8.2 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Endochin is an antimalarial agent, inhibits T. gondii growth in vitro (IC50=0.003 nM), inhibits  inhibited T.gondii cytochrome c reduction with IC50 of 8.2 nM.
Endochin and is effective against acute and latent toxoplasmosis in mice.
Endochin is highly active against the cyst form of T. gondii in mice at low doses, reducing cyst burden by 76-88% after 16 d of treatment.

物理化学性质&存储条件

分子量 287.40
分子式 C18H25NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-Heptyl-7-methoxy-2-methylquinolin-4(1H)-one

参考文献

1. Doggett JS, et al. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15936-41.

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