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首页-小分子抑制剂&激动剂-GPCR-Prostaglandin Receptor-EP2 receptor antagonist CJ-18
EP2 receptor antagonist CJ-18

Chemical Structure : EP2 receptor antagonist CJ-18

CAS No.:

EP2 receptor antagonist CJ-18

货号: PC-28504Not For Human Use, Lab Use Only.

EP2 receptor antagonist CJ-18 is a highly potent, brain-penetrant EP2 receptor antagonist with Kb value of 5.0 nM, reduces ischaemic brain injury by modulating neuroinflammation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

EP2 receptor antagonist CJ-18 is a highly potent, brain-penetrant EP2 receptor antagonist with Kb value of 5.0 nM, reduces ischaemic brain injury by modulating neuroinflammation.

物理化学性质&存储条件

分子量 385.47
分子式 C23H23N5O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-(2-methyl-1H-indol-3-yl)ethyl)-6-((6-methylpyridin-2-yl)amino)nicotinamide

参考文献

1. Jin Z, et al. Br J Pharmacol. 2026 Oct 13. doi: 10.1111/bph.70709.

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