ELOVL6 inhibitor 1w | ELOVL6 inhibitor | Probechem Biochemicals

Chemical Structure : ELOVL6 inhibitor 1w

CAS No.: 1170321-92-2

加入收藏

ELOVL6 inhibitor 1w (ELOVL6-IN-4)

货号: PC-25568Not For Human Use, Lab Use Only.

ELOVL6 inhibitor 1w (ELOVL6-IN-4) is a potent, selective, and orally available ELOVL6 (long chain fatty acid elongase 6) inhibitor with IC50 of 79 and 94 nM for human and mouse ELOVL6 respectively.

规格	价格	库存
5 mg	￥1580	In stock
10 mg	￥2480	In stock
25 mg	￥3980	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

ELOVL6 inhibitor 1w (ELOVL6-IN-4) is a potent, selective, and orally available ELOVL6 (long chain fatty acid elongase 6) inhibitor with IC50 of 79 and 94 nM for human and mouse ELOVL6 respectively.
ELOVL6 inhibitor 1w shows high selectivity over the other ELOVL subtypes ELOVL1,2,5 (IC50>5 uM) and mouse ELOVL3 (IC50>10 uM).
ELOVL6 inhibitor 1w effectively reduced the elongation index with IC50 of 30 nM in mouse hepatocyte cell H2.35 assay.
ELOVL6 inhibitor 1w (1-10 mg/kg, p.o.) potently and dose-dependently suppressed the elongation index in the liver in mice.

物理化学性质&存储条件

分子量	439.45
分子式	C20H20F3N3O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(Pyridin-2-ylsulfonyl)-N-(4-(trifluoromethyl)phenyl)-8-azabicyclo[3.2.1]octane-8-carboxamide-endo

参考文献

1. Tsuyoshi Nagase, et al. J Med Chem. 2009 Jul 23;52(14):4111-4.

ELOVL6 inhibitor 1w (ELOVL6-IN-4)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

ELOVL6 inhibitor 1w (ELOVL6-IN-4)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.