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首页-小分子抑制剂&激动剂-GPCR-Glucagon Receptor-Dulaglutide
Dulaglutide

Chemical Structure : Dulaglutide

CAS No.: 923950-08-7

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Dulaglutide (LY2189265, LY-2189265)

货号: PC-27453Not For Human Use, Lab Use Only.

Dulaglutide (LY2189265) is a long-acting glucagon-like peptide-1 analog and GLP-1 receptor agonist, shows full receptor activity in vitro and elicits insulinotropic activity in islets similar to native peptide, increases glucose tolerance.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Dulaglutide (LY2189265) is a long-acting glucagon-like peptide-1 analog and GLP-1 receptor agonist, shows full receptor activity in vitro and elicits insulinotropic activity in islets similar to native peptide, increases glucose tolerance.

物理化学性质&存储条件

分子量 62561 (Glycosylation, Dominant form)
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

DPP-IV-protected GLP-1(7–37) analogue fused to a modified immunoglobulin G (IgG4) Fc fragment

参考文献

1. Skrivanek Z, et al. J Diabetes Sci Technol. 2012 Nov 1;6(6):1305-18.

2. Barrington P, et al. Diabetes Obes Metab. 2011 May;13(5):434-8.

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