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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Dynamin-Drpitor1
Drpitor1

Chemical Structure : Drpitor1

CAS No.: 73540-73-5

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Drpitor1

货号: PC-26857Not For Human Use, Lab Use Only.

Drpitor1 is a selective, potent dynamin-related protein 1 (Drp1) inhibitor with IC50 of 0.09 uM for mitochondrial fragmentation, inhibits the GTPase activity of Drp1 without inhibiting the GTPase of dynamin 1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Drpitor1 is a selective, potent dynamin-related protein 1 (Drp1) inhibitor with IC50 of 0.09 uM for mitochondrial fragmentation, inhibits the GTPase activity of Drp1 without inhibiting the GTPase of dynamin 1.

物理化学性质&存储条件

分子量 292.29
分子式 C17H12N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-(methoxymethyl)-5H-pyrido[4,3-b]carbazole-5,11(6H)-dione

参考文献

1. Danchen Wu, et al. FASEB J. 2020 Jan;34(1):1447-1464.

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