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首页-小分子抑制剂&激动剂-Apoptosis-Ferroptosis-Deferoxamine
Deferoxamine

Chemical Structure : Deferoxamine

CAS No.: 70-51-9

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Deferoxamine (Deferoxamine B, DFO)

货号: PC-25537Not For Human Use, Lab Use Only.

Deferoxamine (DFO) is a small molecule iron chelator and ferroptosis inhibitor, upregulates HIF-1α levels with good antioxidant activity, also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells.

规格 价格 库存 数量
5 mg ￥1880 In stock
10 mg ￥2980 In stock
25 mg ￥4580 In stock
50 mg Get quote
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Deferoxamine (DFO) is a small molecule iron chelator and ferroptosis inhibitor, upregulates HIF-1α levels with good antioxidant activity, also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells.

物理化学性质&存储条件

分子量 560.69
分子式 C25H48N6O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N1-(5-Aminopentyl)-N1-hydroxy-N4-(5-(N-hydroxy-4-((5-(N-hydroxyacetamido)pentyl)amino)-4-oxobutanamido)pentyl)succinamide

参考文献

1. Christophe Louandre, et al. Int J Cancer. 2013 Oct 1;133(7):1732-42.

2. Dongiovanni P, et al. Am J Pathol. 2008 Mar;172(3):738-47.

3. Wu Y, et al. Neurochem Int. 2010 Oct;57(3):198-205.

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