Decoglurant (RO4995819)

Chemical Structure : Decoglurant

CAS No.: 911115-16-7

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货号: PC-73234Not For Human Use, Lab Use Only.

Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 with antidepressant effect.

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Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 with antidepressant effect.

分子量	447.34
分子式	C21H11F6N5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-((7-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)ethynyl)pyridin-2-amine

1. Wilkinson ST, et al. Drug Discov Today. 2019 Feb;24(2):606-615.

2. Umbricht D, et al. J Clin Psychiatry. 2020 Jul 14;81(4):18m12470.