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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-DNA gyrase inhibitor 35
DNA gyrase inhibitor 35

Chemical Structure : DNA gyrase inhibitor 35

CAS No.: 2088347-91-3

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DNA gyrase inhibitor 35

货号: PC-24340Not For Human Use, Lab Use Only.

DNA gyrase inhibitor 35 is potent small molecule DNA gyrase inhibitor with IC50 of 1.2 μM of E.coli DNA gyrase, also shows low micromolar inhibition of E. coli topoisomerase IV and of the respective Staphylococcus aureus homologues.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

DNA gyrase inhibitor 35 is potent small molecule DNA gyrase inhibitor with IC50 of 1.2 μM of E.coli DNA gyrase, also shows low micromolar inhibition of E. coli topoisomerase IV and of the respective Staphylococcus aureus homologues.

物理化学性质&存储条件

分子量 396.18
分子式 C15H11Cl2N5O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-((4-(3,4-dichloro-5-methyl-1H-pyrrole-2-carboxamido)phenyl)amino)-1,2,4-oxadiazole-3-carboxylic acid

参考文献

1. Jakopin Ž, et al. Eur J Med Chem. 2017 Apr 21;130:171-184.

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