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首页-小分子抑制剂&激动剂-Others-Other Targets-DIBDO
DIBDO

Chemical Structure : DIBDO

CAS No.: 62994-00-7

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DIBDO

货号: PC-27435Not For Human Use, Lab Use Only.

DIBDO is a small molecule gasdermin D (GSDMD) agonist, directly activates GSDMD bypassing Caspase-3, blocks Caspase-3 activation and induces GSDMD‐mediated pyroptosis in tumor cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

DIBDO is a small molecule gasdermin D (GSDMD) agonist, directly activates GSDMD bypassing Caspase-3, blocks Caspase-3 activation and induces GSDMD‐mediated pyroptosis in tumor cells.

物理化学性质&存储条件

分子量 339.90
分子式 C4H6I2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-2,3-diiodobut-2-ene-1,4-diol

参考文献

1. Zhao D, et al. Adv Sci (Weinh). 2026 Jul 23:e76655.

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