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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-DNA Repair Protein -DHX33 inhibitor BCD38
DHX33 inhibitor BCD38

Chemical Structure : DHX33 inhibitor BCD38

CAS No.: 2952895-98-4

DHX33 inhibitor BCD38

货号: PC-26990Not For Human Use, Lab Use Only.

BCD38 is a small molecule inhibitor of RNA helicase DHX33, suppresses the helicase activity of DHX33 in vitro, induces similar effects as DHX33 knockdown.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BCD38 is a small molecule inhibitor of RNA helicase DHX33, suppresses the helicase activity of DHX33 in vitro, induces similar effects as DHX33 knockdown.
BCD38 inhibits cell proliferation, cell survival, anchorage-independent growth and cell migration in lung cancer cell lines, A549 and H1299.

物理化学性质&存储条件

分子量 381.44
分子式 C23H19N5O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-2-(3-(2-(1H-benzo[d]imidazol-2-yl)-2-cyanovinyl)-2,5-dimethyl-1H-pyrrol-1-yl)-4,5-dimethylfuran-3-carbonitrile

参考文献

1. Xingshun Wang, et al. Sci Rep. 2026 Jun 5. doi: 10.1038/s41598-026-55801-5.

2. Wang Y, et al. Bioorg Med Chem Lett. 2023;96:129505.

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