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首页-小分子抑制剂&激动剂-Others-Other Targets-DDAH1 inhibitor 8
DDAH1 inhibitor 8

Chemical Structure : DDAH1 inhibitor 8

CAS No.: 1229238-70-3

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DDAH1 inhibitor 8

货号: PC-49750Not For Human Use, Lab Use Only.

DDAH1 inhibitor 8 is a potent, selective, nonamino acid, catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) with Ki of 18 uM, with no significantly affecting NOSs and arginase.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    DDAH1 inhibitor 8 is a potent, selective, nonamino acid, catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) with Ki of 18 uM, with no significantly affecting NOSs and arginase.

    物理化学性质&存储条件

    分子量 416.32
    分子式 C12H22F6N4O5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    Guanidine, N-(4-aminobutyl)-N′-(2-methoxyethyl)-, 2,2,2-trifluoroacetate (1:2)

    参考文献

    1. Ina Lunk, et al. J Med Chem. 2020 Jan 9;63(1):425-432.

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