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首页-小分子抑制剂&激动剂-GPCR-Glucagon Receptor-DD202-114
DD202-114

Chemical Structure : DD202-114

CAS No.: 2886728-09-0

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DD202-114 (HDM1002)

货号: PC-24418Not For Human Use, Lab Use Only.

DD202-114 (HDM1002) is a potent and selective glucagon-like peptide-1 receptor (GLP-1R) agonist with EC50 of 0.03 nM in cAMP assay in HEK293 cells expressing hGLP-1R.

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5 mg ￥1480 In stock
10 mg ￥2380 In stock
25 mg ￥3980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

DD202-114 (HDM1002) is a potent and selective glucagon-like peptide-1 receptor (GLP-1R) agonist with EC50 of 0.03 nM in cAMP assay in HEK293 cells expressing hGLP-1R.

物理化学性质&存储条件

分子量 586.66
分子式 C33H35FN4O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-2-((4-(6-((2-Fluoro-4-(oxetan-3-yl)benzyl)oxy)pyridin-2-yl)piperidin-1-yl)methyl)-1-(oxetan-2-ylmethyl)-1H-benzo[d]imidazole-6-carboxylic acid

参考文献

1. Zhimin Zhang, et al. J Med Chem. 2024 Sep 12;67(17):14820-14839.

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