欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-DCY1040
DCY1040

Chemical Structure : DCY1040

CAS No.:

加入收藏

DCY1040 (DCY-1040)

货号: PC-25469Not For Human Use, Lab Use Only.

DCY1040 is a potent, specific small molecule agonist of transmembrane protein 175 (TMEM175) with EC50 of 3.0 uM and 105.9-fold potentiation, directly binds to TMEM175.

规格 价格 库存 数量
50 mg Get quote
100 mg Get quote
250 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

DCY1040 is a potent, specific small molecule agonist of transmembrane protein 175 (TMEM175) with EC50 of 3.0 uM and 105.9-fold potentiation, directly binds to TMEM175.
DCY1040 and TUG-891 synergistically activate TMEM175
DCY1040 activates TMEM175 more effectively than DCPIB (Cat# PC-72941).
DCY1040 restores PD-related variants in TMEM175.
DCY1040 promotes the removal of aberrant α-synuclein both in vitro and in vivo.

物理化学性质&存储条件

分子量 418.49
分子式 C22H28F2N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-(3-(1H-tetrazol-5-yl)propoxy)-2-butyl-2-cyclopentyl-6,7-difluoro-2,3-dihydro-1H-inden-1-one

参考文献

1. Xuewu Zhu, et al. Structural insights into the activation of TMEM175 by small molecule. Neuron. 2025 Aug 22:S0896-6273(25)00556-2.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: