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首页-抗体药物偶连体和PROTACs-E3 Ligase Ligand-DCAF1 ligand 1
DCAF1 ligand 1

Chemical Structure : DCAF1 ligand 1

CAS No.: 3053860-67-3

DCAF1 ligand 1 (DCAF1 E3 ligase binder 1)

货号: PC-21643Not For Human Use, Lab Use Only.

DCAF1 ligand 1 is a selective DCAF1 E3 ligase receptor binder with SPR KD value of 0.03 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    DCAF1 ligand 1 is a selective DCAF1 E3 ligase receptor binder with SPR KD value of 0.03 uM.
    DCAF1 E3 ligase binder 1 shows only partial overlap with recently reported DCAF1 ligand OICR-8268 (Cat# PC-20292).
    DCAF1 E3 ligase binder 1 displays no activity against any other WDR-containing proteins.

    物理化学性质&存储条件

    分子量 507.08
    分子式 C28H35ClN6O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-(4-(4-((2-aminoethyl)amino)-2-(1-(4-chlorophenyl)cyclohexyl)quinazolin-7-yl)piperazin-1-yl)ethan-1-one

    参考文献

    1. Schröder M, et al. Nat Commun. 2024 Jan 4;15(1):275.

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