Chemical Structure : DC-U43-10
CAS No.: 2477650-96-5
货号: PC-26962Not For Human Use, Lab Use Only.
DC-U43-10 (USP8-IN-1) is a specific small molecule USP8 inhibitor with IC50 of 2.6 uM, exhibits 10-fold selectivity against USP7.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | ¥1580 | In stock | |
| 10 mg | ¥2480 | In stock | |
| 25 mg | ¥3980 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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DC-U43-10 (USP8-IN-1) is a specific small molecule USP8 inhibitor with IC50 of 2.6 uM, exhibits 10-fold selectivity against USP7.
DC-U43-10 has KD of 10.5 uM in surface plasmon resonance (SPR) assays.
DC-U43-10 inhibits the colony formation of H1975 cells with EC50 of 30.8 uM.
| 分子量 | 387.46 | |
| 分子式 | C18H21N5O3S | |
| 外观性状 | Solid | |
| 储存条件 |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)piperazine-1-carbothioamide |
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1. Jie Han, et al. Bioorg Chem. 2020 Aug:101:103962.
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