DC-BPi-11 hydrochloride

Chemical Structure : DC-BPi-11 hydrochloride

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货号: PC-28097Not For Human Use, Lab Use Only.

DC-BPi-11 hydrochloride is a potent, high affinity, selective BPTF bromodomain inhibitor with IC50 of 26.9 nM in HTRF assays and SPR KD of 20.7 nM, shows >100-fold selectivity over other BRD targets.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

DC-BPi-11 hydrochloride is a potent, high affinity, selective BPTF bromodomain inhibitor with IC50 of 26.9 nM in HTRF assays and SPR KD of 20.7 nM, shows >100-fold selectivity over other BRD targets.

物理化学性质&存储条件

分子量	433.96
分子式	C20H24ClN5O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N,N-Dimethyl-3-(5-(2-(methylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-indol-1-yl)propan-1-amine hydrochloride

参考文献

1. Lu T, et al. J Med Chem. 2021 Aug 26;64(16):12075-12088.