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首页-小分子抑制剂&激动剂-Epigenetics-Bromodomain-DC-BPi-11
DC-BPi-11

Chemical Structure : DC-BPi-11

CAS No.: 2758411-61-7

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DC-BPi-11

货号: PC-28096Not For Human Use, Lab Use Only.

DC-BPi-11 is a potent, high affinity, selective BPTF bromodomain with IC50 of 26.9 nM in HTRF assays and SPR KD of 20.7 nM, shows >100-fold selectivity over other BRD targets.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

DC-BPi-11 is a potent, high affinity, selective BPTF bromodomain with IC50 of 26.9 nM in HTRF assays and SPR KD of 20.7 nM, shows >100-fold selectivity over other BRD targets.

物理化学性质&存储条件

分子量 397.50
分子式 C20H23N5O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N,N-Dimethyl-3-(5-(2-(methylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-indol-1-yl)propan-1-amine

参考文献

1. Lu T, et al. J Med Chem. 2021 Aug 26;64(16):12075-12088.

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