Chemical Structure : DC-517
CAS No.: 500017-70-9
货号: PC-43175Not For Human Use, Lab Use Only.
DC-517 is a potent, selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 1.7 uM, displays significant selectivity toward other AdoMet-dependent protein methyltransferases.
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DC-517 is a potent, selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 1.7 uM, displays significant selectivity toward other AdoMet-dependent protein methyltransferases.
DC-517 significantly inhibits cancer cell proliferation in vitro.
分子量 | 505.6499 | |
分子式 | C33H35N3O2 | |
外观性状 | Solid | |
储存条件 |
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|
Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-Propanol, 1-[2-(9H-carbazol-9-yl)-1-(9H-carbazol-9-ylmethyl)ethoxy]-3-[(1-methylethyl)amino]- |
1. Chen S, et al. J Med Chem. 2014 Nov 13;57(21):9028-41.
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