DC-517 (DC517, DC_517)

Chemical Structure : DC-517

CAS No.: 500017-70-9

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货号: PC-43175Not For Human Use, Lab Use Only.

DC-517 (DC517, DC_517) is a potent, selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 1.7 uM, displays significant selectivity toward other AdoMet-dependent protein methyltransferases.

规格	价格	库存
5 mg	￥1580	In stock
10 mg	￥2480	In stock
25 mg	￥3980	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

DC-517 (DC517, DC_517) is a potent, selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 1.7 uM, displays significant selectivity toward other AdoMet-dependent protein methyltransferases.
DC-517 significantly inhibits cancer cell proliferation in vitro.

物理化学性质&存储条件

分子量	505.6499
分子式	C33H35N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Propanol, 1-[2-(9H-carbazol-9-yl)-1-(9H-carbazol-9-ylmethyl)ethoxy]-3-[(1-methylethyl)amino]-

参考文献

1. Chen S, et al. J Med Chem. 2014 Nov 13;57(21):9028-41.