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首页-抗体药物偶连体和PROTACs-ADCs Linker/Click Chemistry-DBCO-NHS ester
DBCO-NHS ester

Chemical Structure : DBCO-NHS ester

CAS No.: 1353016-71-3

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DBCO-NHS ester (DBCO NHS ester)

货号: PC-70081Not For Human Use, Lab Use Only.

DBCO-NHS ester is an amine-reactive NHS ester as ADC linker that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.

规格 价格 库存 数量
25 mg ￥880 In stock
50 mg ￥1280 In stock
100 mg ￥1980 In stock
500 mg ￥3980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

DBCO-NHS ester is an amine-reactive NHS ester as ADC linker that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.
DBCO-NHS ester is a click chemistry tool used to conjugate DBCO-PEG4-MMAF to the introduced non-natural amino acid pAMF using a noncleavable linker.

物理化学性质&存储条件

分子量 430.45
分子式 C25H22N2O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Dibenz[b,f]azocine-5(6H)-butanoic acid,11,12-didehydro-γ-oxo-,2,5-dioxo-1-pyrrolidinyl es

参考文献

1. Currier NV, et al. Mol Cancer Ther. 2016 Jun;15(6):1291-300.

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