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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Glutamate Transporter-DA-023
DA-023

Chemical Structure : DA-023

CAS No.: 2585643-97-4

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DA-023 (DA023)

货号: PC-28284Not For Human Use, Lab Use Only.

DA-023 is a potent, selective positive allosteric modulator (PAM) of excitatory amino acid transporter 2 (EAAT2) with EC50 of 1.0 nM, is inactive against EAAT1 and EAAT3.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

DA-023 is a potent, selective positive allosteric modulator (PAM) of excitatory amino acid transporter 2 (EAAT2) with EC50 of 1.0 nM, is inactive against EAAT1 and EAAT3.

物理化学性质&存储条件

分子量 363.46
分子式 C20H25N7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-methyl-4-((1-phenethyl-1H-tetrazol-5-yl)(pyridin-3-yl)methyl)piperazine

参考文献

1. Fontana ACK, et al. J Med Chem. 2024 Apr 25;67(8):6119-6143.

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