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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-D-IX216
D-IX216

Chemical Structure : D-IX216

CAS No.: 1803031-82-4

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D-IX216

货号: PC-25641Not For Human Use, Lab Use Only.

D-IX216 is a potent, selective Mycobacterial RNA polymerase (Mtb RNAP) with IC50 of 100 nM, slows MtbRNAP translocation in a sequence-independent manner.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

D-IX216 is a potent, selective Mycobacterial RNA polymerase (Mtb RNAP) with IC50 of 100 nM, slows MtbRNAP translocation in a sequence-independent manner.

物理化学性质&存储条件

分子量 452.55
分子式 C24H25FN4O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(1-((5-fluoro-2-(piperazin-1-yl)phenyl)amino)-1-oxo-3-phenylpropan-2-yl)thiophene-2-carboxamide

参考文献

1. Herrera-Asmat O, et al. Elife. 2025 Oct 3;14:e105545.

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