D-AAP1

Chemical Structure : D-AAP1

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货号: PC-25640Not For Human Use, Lab Use Only.

D-AAP1 is a potent, selective, stereospecific activity against Mycobacterium tuberculosis RNA polymerase (Mtb RNAP) with IC50 of 0.4 uM, shows poor inhibition of other bacterial RNAP and human RNAP I, II, and III.

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D-AAP1 is a potent, selective, stereospecific activity against Mycobacterium tuberculosis RNA polymerase (Mtb RNAP) with IC50 of 0.4 uM, shows poor inhibition of other bacterial RNAP and human RNAP I, II, and III.
D-AAP1 exhibits potent, selective, stereospecific activity against Mycobacteria (potent activity against Mtb, M. avium, and M. smegmatis, but poor activity against other bacterial and mammalian cells).

物理化学性质&存储条件

分子量	358.44
分子式	C23H22N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N-(1-oxo-3-phenyl-1-(o-tolylamino)propan-2-yl)benzamide

参考文献

1. Wei Lin, et al. Mol Cell. 2017 Apr 20;66(2):169-179.e8.

D-AAP1

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D-AAP1

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