欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-抗体和重组蛋白-Biosimilar Antibody-Cusatuzumab
Cusatuzumab

Chemical Structure : Cusatuzumab

CAS No.: 1399546-01-0

加入收藏

Cusatuzumab (Anti-human CD70 mAb, human IgG1-Lambda2; ARGX-110)

货号: PC-Ab1038Not For Human Use, Lab Use Only.

Cusatuzumab (ARGX-110) is a human αCD70 monoclonal antibody with enhanced antibody-dependent cellular cytotoxicity activity, eliminated LSCs in vitro and in xenotransplantation experiments. Cusatuzumab triggers Fc-mediated cytotoxicity with enhanced ADCC and inhibition of CD70/CD27 signaling, resulting in killing of malignant cells such as leukemia blasts and stem cells..

规格 价格 库存 数量
1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Cusatuzumab (ARGX-110) is a human αCD70 monoclonal antibody with enhanced antibody-dependent cellular cytotoxicity activity, eliminated LSCs in vitro and in xenotransplantation experiments. Cusatuzumab triggers Fc-mediated cytotoxicity with enhanced ADCC and inhibition of CD70/CD27 signaling, resulting in killing of malignant cells such as leukemia blasts and stem cells.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Lambda2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Cusatuzumab; ARGX-110; ARGX110; 1399546-01-0; Cluster of Differentiation 70; CD70.

参考文献

1. 1, Riether C, et al. Nat Med. 2020 Sep;26(9):1459-1467. 2, The CD70 Antibody Cusatuzumab Shows Promise in Acute Myeloid Leukemia. Cancer Discov. 2020 Sep;10(9):1251. 3, Leupin N, et al. Cancer. 2021 Nov 2. doi: 10.1002/cncr.34005. 4, Venugopal S, et al. Curr Hematol Malig Rep. 2021 Feb;16(1):89-96.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: