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首页-小分子抑制剂&激动剂-Others-Other Targets-Conoidin A
Conoidin A

Chemical Structure : Conoidin A

CAS No.: 18080-67-6

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Conoidin A

货号: PC-25316Not For Human Use, Lab Use Only.

Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties, covalently binds to the peroxidatic Cys47 of TgPrxII and inhibits its hyperperoxidation activity with IC50 of 23 uM, also is a small molecule peroxiredoxin 1 (PRDX1) inhibitor with IC50 of 14.8 uM.

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50 mg ￥580 In stock
100 mg ￥880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties, covalently binds to the peroxidatic Cys47 of TgPrxII and inhibits its hyperperoxidation activity with IC50 of 23 uM, also is a small molecule peroxiredoxin 1 (PRDX1) inhibitor with IC50 of 14.8 uM.

物理化学性质&存储条件

分子量 347.99
分子式 C10H8Br2N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide

参考文献

1. Jeralyn D Haraldsen, et al. Org Biomol Chem. 2009;7:3040-3048.

2. Gu Liu, et al. ChemMedChem. 2010 Jan;5(1):41-5.

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