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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Gap Junction Protein-Connexin 43 inhibitor Gap 26
Connexin 43 inhibitor Gap 26

Chemical Structure : Connexin 43 inhibitor Gap 26

CAS No.: 197250-15-0

Connexin 43 inhibitor Gap 26 (Gap26)

货号: PC-25862Not For Human Use, Lab Use Only.

Connexin 43 inhibitor Gap 26 (Gap26) is a connexin mimetic peptide inhibitor of Connexin 43 (Cx43), inhibits Gap junctions (GJs), confers protection to intact heart against myocardial ischemia injury.

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5 mg ¥1280 In stock
10 mg ¥1980 In stock
25 mg ¥3580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Connexin 43 inhibitor Gap 26 (Gap26) is a connexin mimetic peptide inhibitor of Connexin 43 (Cx43), inhibits Gap junctions (GJs), blocks the electrical connection between cells facilitated by GJs, confers protection to intact heart against myocardial ischemia injury.

物理化学性质&存储条件

分子量 1550.80
分子式 C70H107N19O19S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Val-Cys-Tyr-Asp-Lys-Ser-Phe-Pro-Ile-Ser-His-Val-Arg

参考文献

1. Mohammed D, et al. Cureus. 2024 Apr 26;16(4):e59053.

2. Hawat G, et al. Pflugers Arch. 2010 Aug;460(3):583-92.

3. Pearson RA, et al. J Neurosci. 2005 Nov 16;25(46):10803-14.

4. Braet K, et al. Cell Calcium 33: 37-48.

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