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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-Clozapine
Clozapine

Chemical Structure : Clozapine

CAS No.: 5786-21-0

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Clozapine (HF 1854)

货号: PC-43961Not For Human Use, Lab Use Only.

An atypical antipsychotic agent that binds to 5-HT and dopamine receptor.

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500 mg ￥720 In stock
5 g ￥2000 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM; mainly used for schizophrenia.

Schizophrenia

Approved

物理化学性质&存储条件

分子量 326.8233
分子式 C18H19ClN4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-

参考文献

1. Seeman P, et al. ACS Chem Neurosci. 2014 Jan 15;5(1):24-9.

2. Zhukovskaya NL, et al. Neurosci Lett. 2000 Jul 21;288(3):236-40.

3. Moreno JL, et al. Psychopharmacology (Berl). 2013 Jan;225(1):217-26.

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