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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HBV-Clevudine
Clevudine

Chemical Structure : Clevudine

CAS No.: 163252-36-6

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Clevudine (L-FMAU)

货号: PC-28208Not For Human Use, Lab Use Only.

Clevudine (L-FMAU) is a nucleoside analog and non-competitive, reverse transcriptase inhibitor, inhibits both protein priming and DNA elongation, has potent anti-HBV activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Clevudine (L-FMAU) is a nucleoside analog and non-competitive, reverse transcriptase inhibitor, inhibits both protein priming and DNA elongation, has potent anti-HBV activity.

物理化学性质&存储条件

分子量 260.22
分子式 C10H13FN2O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-((2S,3R,4S,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

参考文献

1. Asselah T, et al. Expert Opin Investig Drugs. 2008;17(12):1963-1974.

2. Yoo BC, et al. Hepatology. 2007;46(4):1041-1048.

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