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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-CMV-Cidofovir
Cidofovir

Chemical Structure : Cidofovir

CAS No.: 113852-37-2

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Cidofovir (GS0504, HPMPC, (S)-HPMPC)

货号: PC-45259Not For Human Use, Lab Use Only.

Cidofovir (GS-0504, HPMPC) is the prodrug of cidofovir diphosphate that inhibits cytomegalovirus (CMV) viral replication by selectively inhibiting viral DNA polymerases.

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100 mg ￥880 In stock
250 mg ￥1380 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Cidofovir (GS-0504, HPMPC) is the prodrug of cidofovir diphosphate that inhibits cytomegalovirus (CMV) viral replication by selectively inhibiting viral DNA polymerases.
Cidofovir also incorporates itself into viral DNA hence inhibiting viral DNA synthesis during reproduction.

物理化学性质&存储条件

分子量 279.187
分子式 C8H14N3O6P
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

H2O: 6.4 mg/mL (Need warming)
Chemical Name/SMILES

Phosphonic acid, P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-

参考文献

1, David J Maggs, et al. Am J Vet Res. 2004 Apr;65(4):399-403.
2. Robert O Baker, et al. Antiviral Res. 2003 Jan;57(1-2):13-23.

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