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首页-抗体和重组蛋白-Biosimilar Antibody-Cibisatamab
Cibisatamab

Chemical Structure : Cibisatamab

CAS No.: 2101242-53-7

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Cibisatamab (Anti-human CEACAM5 mAb, human IgG1-Kappa; RG-7802)

货号: PC-Ab1057Not For Human Use, Lab Use Only.

Cibisatamab (CEA-TCB, RO-6958688) is a novel bispecific antibody immunotherapy that effectively brings the cancer cells and cancer-killing T cells of the immune system together, triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cell surface. It is efficacious in poorly infiltrated tumors where it increases T-cell infiltration and generates a highly inflamed tumor microenvironment..

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1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Cibisatamab (CEA-TCB, RO-6958688) is a novel bispecific antibody immunotherapy that effectively brings the cancer cells and cancer-killing T cells of the immune system together, triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cell surface. It is efficacious in poorly infiltrated tumors where it increases T-cell infiltration and generates a highly inflamed tumor microenvironment.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Cibisatamab; CEA-CD3 TCB; CEA-TCB; RG-7802; RO-6958688; CD66e; Carcinoembryonic antigen (CEA); CEACAM5; 2101242-53-7

参考文献

1. 1, Van De Vyver AJ, et al. Mol Cancer Ther. 2021 Feb;20(2):357-366. 2, Gonzalez-Exposito R, et al. J Immunother Cancer. 2019 Apr 15;7(1):101. 3, Marina Bacac, et al. Clin Cancer Res . 2016 Jul 1;22(13):3286-97.

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