Chenodeoxycholic Acid |CAS:474-25-9 Probechem Biochemicals

Chemical Structure : Chenodeoxycholic Acid

CAS No.: 474-25-9

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Chenodeoxycholic Acid (CDCA)

货号: PC-45980Not For Human Use, Lab Use Only.

Chenodeoxycholic Acid (CDDA) is a potent natural bile acid at stimulating the nuclear bile acid receptor, farnesoid X receptor (FXR).

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100 mg	￥580	In stock
250 mg	￥980	In stock
1 g		Get quote

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生物&药学活性

Chenodeoxycholic Acid (CDDA) is a potent natural bile acid at stimulating the nuclear bile acid receptor, farnesoid X receptor (FXR).
CDDA increases plasma concentrations of GLP-1, C-peptide, glucagon, peptide YY, neurotensin, total bile acids, and FGF19 significantly compared with placebo.
CDDA also activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis.

物理化学性质&存储条件

分子量	392.572
分子式	C24H40O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 3.6 mg/mL
Chemical Name/SMILES	Cholan-24-oic acid, 3,7-dihydroxy-, (3α,5β,7α)-

参考文献

1. Parks DJ, et al. Science. 1999 May 21;284(5418):1365-8.

2. Nielsen S, et al. Physiol Rep. 2017 Feb;5(3). pii: e13140.

3. Gong Z, et al. Oncotarget. 2016 Dec 20;7(51):83951-83963.

Chenodeoxycholic Acid (CDCA)

生物&药学活性

物理化学性质&存储条件

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Chenodeoxycholic Acid (CDCA)

生物&药学活性

物理化学性质&存储条件

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