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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Monoamine Transporter-Centanafadine hydrochloride
Centanafadine hydrochloride

Chemical Structure : Centanafadine hydrochloride

CAS No.: 923981-14-0

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Centanafadine hydrochloride (EB-1020 hydrochloride)

货号: PC-27839Not For Human Use, Lab Use Only.

Centanafadine hydrochloride (EB-1020 hydrochloride) is a potent triple reuptake inhibitor of reuptake transporters for norepinephrine (NET), dopamine (DAT) and serotonin (SERT) with IC50 of 6 nM, 38 nM and 83 nM respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Centanafadine hydrochloride (EB-1020 hydrochloride) is a potent triple reuptake inhibitor of reuptake transporters for norepinephrine (NET), dopamine (DAT) and serotonin (SERT) with IC50 of 6 nM, 38 nM and 83 nM respectively.

物理化学性质&存储条件

分子量 245.75
分子式 C15H16ClN
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(1R,5S)-1-(Naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane hydrochloride

参考文献

1. Matuskey D, et al. J Psychopharmacol. 2023 Feb;37(2):164-171.

2. Bymaster FP, et al. Synapse 66: 522–532.

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