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首页-小分子抑制剂&激动剂-GPCR-Lysophospholipid Receptor-Cenerimod
Cenerimod

Chemical Structure : Cenerimod

CAS No.: 1262414-04-9

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Cenerimod (ACT-334441, ACT334441)

货号: PC-45386Not For Human Use, Lab Use Only.

Cenerimod (ACT-334441) is a potent and orally available S1P1 receptor agonist with EC50 of 2.7 nM.

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5 mg ￥780 In stock
10 mg ￥1180 In stock
25 mg ￥1980 In stock
50 mg ￥3480 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Cenerimod (ACT-334441) is a potent and orally available S1P1 receptor agonist with EC50 of 2.7 nM.
Cenerimod (ACT-334441) shows a powerful and long-lasting immunomodulating effect by reducing the number of circulating and infiltrating T- and B-lymphocytes, without affecting their maturation, memory, or expansion.

物理化学性质&存储条件

分子量 453.5307
分子式 C25H31N3O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1,2-Propanediol, 3-[4-[5-(2-cyclopentyl-6-methoxy-4-pyridinyl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-, (2S)-

参考文献

1. Piali L, et, al. Pharmacol Res Perspect. 2017 Dec;5(6):e00370.

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