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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Cyclin-dependent Kinase (CDK)-Cdk5i peptide
Cdk5i peptide

Chemical Structure : Cdk5i peptide

CAS No.: 2298317-00-5

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Cdk5i peptide (Cdk5/p25 inhibitor peptide ARAFGIPVRCYS)

货号: PC-20494Not For Human Use, Lab Use Only.

Cdk5i peptide is a Cdk5-derived 12-amino acid long Cdk5-derived peptide that interferes with the Cdk5/p25 complex with Kd of 0.17 uM, 40-fold more strongly to either Cdk5 or Cdk2 alone.

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10 mg ￥880 In stock
25 mg ￥1480 In stock
50 mg ￥2480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Cdk5i peptide is a Cdk5-derived 12-amino acid long Cdk5-derived peptide that interferes with the Cdk5/p25 complex with Kd of 0.17 uM, 40-fold more strongly to either Cdk5 or Cdk2 alone.
Cdk5i peptide ameliorates neurodegenerative phenotypes in cell and mouse models of Cdk5 hyperactivity.

物理化学性质&存储条件

分子量 1339.58
分子式 C60H94N18O15S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Sequence: Ala-Arg-Ala-Phe-Gly-Ile-Pro-Val-Arg-Cys-Tyr-Ser

参考文献

1. Ping-Chieh Pao, et al. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2217864120.

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