Cbl-b-IN-1

Chemical Structure : Cbl-b-IN-1

CAS No.: 2368841-84-1

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货号: PC-25785Not For Human Use, Lab Use Only.

Cbl-b-IN-1 is a potent, selective, small molecule inhibitor of E3 ligase Casitas B-lineage lymphoma proto oncogene B (CBL-B) with IC50 of <100 nM, shows binding selectivity over C-CBL.

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5 mg	￥2880	In stock
10 mg	￥4580	In stock
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生物&药学活性

Cbl-b-IN-1 is a potent, selective, small molecule inhibitor of E3 ligase Casitas B-lineage lymphoma proto oncogene B (CBL-B) with IC50 of <100 nM, shows binding selectivity over C-CBL.

物理化学性质&存储条件

分子量	498.63
分子式	C29H34N6O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(5-Azaspiro[2.4]heptan-5-ylmethyl)-6-cyclopropyl-N-(3-(3-((4-methyl-4H-1,2,4-triazol-3-yl)methyl)oxetan-3-yl)phenyl)picolinamide

参考文献

1. Patent WO2024105563 A1.

Cbl-b-IN-1

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物理化学性质&存储条件

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Cbl-b-IN-1

生物&药学活性

物理化学性质&存储条件

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