Caryophyllene oxide (β-caryophyllene oxide) | CAS 1139-30-6

Chemical Structure : Caryophyllene oxide

CAS No.: 1139-30-6

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Caryophyllene oxide (Beta-caryophyllene oxide, (-)-Caryophyllene oxide)

货号: PC-28082Not For Human Use, Lab Use Only.

规格	价格	库存
100 mg	￥320	In stock
250 mg	￥520	In stock
1 g	￥980	In stock
5 g		Get quote

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生物&药学活性

Caryophyllene oxide (β-caryophyllene oxide, beta-caryophyllene oxide) is a naturally occurring sesquiterpene component of many essential oils, acts as a chemosensitizer in hepatocellular carcinoma by inhibiting ABCB1, MRP1, and MRP2.
Caryophyllene oxide induces apoptosis and inhibits proliferation of A549 lung cancer cells.
Caryophyllene oxide markedly reduced BCRP-induced resistance to known substrate drugs (mitoxantrone and SN-38) and cisplatin, gemcitabine, sorafenib, and 5-FU but not oxaliplatin.
Caryophyllene oxide exhibits insecticidal, antioxidant, antimicrobial, antifungal, and antiparasitic properties.

物理化学性质&存储条件

分子量	220.36
分子式	C15H24O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1R,4R,6R,10S)-4,12,12-Trimethyl-9-methylene-5-oxatricyclo[8.2.0.04,6]dodecane

参考文献

1. Sain S, et al. Antiinflamm Antiallergy Agents Med Chem. 2014 Mar;13(1):45-55.

2. Ortiz-Rivero S, et al. Biomed Pharmacother. 2024 Jan;170:116038.

3. Ramírez-Santos J, et al. Int J Mol Sci. 2024 Dec 12;25(24):13355.

Caryophyllene oxide (Beta-caryophyllene oxide, (-)-Caryophyllene oxide)

生物&药学活性

物理化学性质&存储条件

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Caryophyllene oxide (Beta-caryophyllene oxide, (-)-Caryophyllene oxide)

生物&药学活性

物理化学性质&存储条件

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