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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Sodium Channel-Carbamazepine
Carbamazepine

Chemical Structure : Carbamazepine

CAS No.: 298-46-4

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Carbamazepine (NSC 169864)

货号: PC-27929Not For Human Use, Lab Use Only.

Carbamazepine (NSC 169864) is an orally active pressure-sensitive sodium ion channel blocker, blocks voltage gated Na+, Ca2+, and K+ channels, and is also a HDAC inhibitor (IC50=2 uM), is an anticonvulsant.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Carbamazepine (NSC 169864) is an orally active pressure-sensitive sodium ion channel blocker, blocks voltage gated Na+, Ca2+, and K+ channels, and is also a HDAC inhibitor (IC50=2 uM), is an anticonvulsant.

物理化学性质&存储条件

分子量 236.27
分子式 C15H12N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5H-Dibenzo[b,f]azepine-5-carboxamide

参考文献

1. Willow, M, et al. Mol Pharmacol, 1982. 22(3): p. 627-35.

2. Okada, M., et al. Epilepsy Res, 1997. 28(2): p. 143-53.

3. Beutler AS, et al. Life Sci. 2005 May 13;76(26):3107-15.

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