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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Angiotensin-converting Enzyme (ACE)-Captopril
Captopril

Chemical Structure : Captopril

CAS No.: 62571-86-2

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Captopril (SQ 14225)

货号: PC-25271Not For Human Use, Lab Use Only.

Captopril (SQ 14225) is antihypertensive agent that acts as a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor with IC50 of 25 nM, is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with IC50 of 7.9 uM.

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50 mg ￥280 In stock
100 mg ￥380 In stock
500 mg ￥580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Captopril (SQ 14225) is antihypertensive agent that acts as a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor with IC50 of 25 nM, is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with IC50 of 7.9 uM.

物理化学性质&存储条件

分子量 217.28
分子式 C9H15NO3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylic acid

参考文献

1. Afrin S, et al. J Agric Food Chem. 2016;64(11):2263-2268.

2. Li N, et al. Bioorg Med Chem Lett. 2014;24(1):386-389.

3. Tzakos, A.G., et al. Bioorg Med Chem Lett, 2006. 16(19): p. 5084-7.

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