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Calpastatin stabilizer A36

Chemical Structure : Calpastatin stabilizer A36

CAS No.: 3110929-05-7

Calpastatin stabilizer A36 (CAST stabilizer A36)

货号: PC-26465Not For Human Use, Lab Use Only.

Calpastatin stabilizer A36 is a brain-penetrant small molecule that selectively stabilizes the calpastatin-calpain-2 complex, restores mitochondrial function and mitigates neurodegeneration.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Calpastatin stabilizer A36 is a brain-penetrant small molecule that selectively stabilizes the calpastatin-calpain-2 complex, restores mitochondrial function and mitigates neurodegeneration.

物理化学性质&存储条件

分子量 471.34
分子式 C22H20Cl2N6O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-(2-((4-(2,4-dichlorophenyl)-5-morpholinopyrimidin-2-yl)amino)ethoxy)nicotinonitrile

参考文献

1. Hu D, et al. Sci Adv. 2026 Mar 27;12(13):eaeb1174.

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