CY-09 | NLRP3 inhibitor | Probechem Biochemicals

Chemical Structure : CY-09

CAS No.: 1073612-91-5

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CY-09 (NLRP3 inhibitor CY-09)

货号: PC-35137Not For Human Use, Lab Use Only.

CY-09 (NLRP3 inhibitor CY-09) is a selective and direct NLRP3 inhibitor, binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 ATPase activity.

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥2980	In stock
100 mg		Get quote

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生物&药学活性

CY-09 (NLRP3 inhibitor CY-09) is a selective and direct NLRP3 inhibitor, binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 ATPase activity.
CY-09 suppresses NLRP3 inflammasome assembly and activation, shows remarkable therapeutic effects on mouse models of cryopyrin-associated autoinflammatory syndrome (CAPS) and type 2 diabetes.

物理化学性质&存储条件

分子量	423.424
分子式	C19H12F3NO3S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzoic acid, 4-[[4-oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]-

参考文献

1. Jiang H, et al. J Exp Med. 2017 Nov 6;214(11):3219-3238.

CY-09 (NLRP3 inhibitor CY-09)

生物&药学活性

物理化学性质&存储条件

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CY-09 (NLRP3 inhibitor CY-09)

生物&药学活性

物理化学性质&存储条件

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