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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Glutaminase-CU1015
CU1015

Chemical Structure : CU1015

CAS No.: 1942072-07-2

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CU1015 (CU-1015)

货号: PC-25410Not For Human Use, Lab Use Only.

CU1015 is a specific inhibitor of kidney-type glutaminase GLS-1 with dual glutaminase inhibition and Nrf2 activation activities, reduces pain sensitization in chemotherapy-induced peripheral neuropathy mouse model.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CU1015 is a specific inhibitor of kidney-type glutaminase GLS-1 with dual glutaminase inhibition and Nrf2 activation activities, reduces pain sensitization in chemotherapy-induced peripheral neuropathy mouse model.

物理化学性质&存储条件

分子量 355.28
分子式 C19H19BrN2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(3-bromo-4-(dimethylamino)benzyl)naphthalen-2-amine

参考文献

1. Pantent WO2016090350 A1.

2. Foster BK, et al. J Pharmacol Exp Ther. 2025 Jun;392(6):103583.

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